• Lavandin
  • Lavandin

Lavandin

  • Scientific Name
    Lavandula X intermedia
  • Family
    Lamiaceae
  • Origin
    Franceetc.

CONTENTS

Plant description

Lavandin is an evergreen plant in the Lamiaceae family. It is a hybrid between true lavender and spike lavender and looks much like lavender. The term “intermedia” in its scientific name signifies its intermediate nature between true lavender and spike lavender. Primarily grown in France, Lavandin is both highly hot and cold resistant and thrives in regions between the lower elevations suitable for spike lavender and the higher elevations ideal for true lavender. Its ability to flourish in a wide range of environments has led to its cultivation in various places, including regions where growing other plants might be challenging. Notably, lavandin is hardier than both true lavender and spike lavender, making it a valuable source for essential oil production due to its higher yield.

Essential oil composition

Lavandin

  • Lavandin

  • INCI
    LAVANDULA HYBRIDA OIL
  • Parts of Plant Used
    Flower
  • Extraction Method
    Steam Distillation
  • Extraction Rate
    1.5% - 2%
  • Notes
    Middle
  • Aroma Family
    Floral

Lavandin Essential Oil Properties & Uses

About 1.5%-2% of Lavandin essential oil is obtained by steam distillation from Lavandin flowers and is colorless to pale yellow in color. Its primary constituents include linalool, known for its relaxing properties, along with linalyl acetate and camphor, among others. Lavandin essential oil is distinguished by its fresher and sweeter aroma compared to lavender essential oil. The fragrance carries the sweetness characteristic of lavender, but also possesses an herbal freshness that sets it apart. This combination of scents makes Lavandin a versatile choice, appealing to those who may not favor lavender. Lavandin essential oil is a key ingredient in various products, particularly in eau de cologne and men's cosmetics. It blends harmoniously with a wide range of other essential oils and pairs exceptionally well with numerous citrus oils. Due to its neutral strength, it's recommended add in amounts that maintain a well-balanced blend.

Essential oil composition

Essential oil composition

※An example of one batch production is shown here.

  • Linalyl acetate　35.28%
  • Linalool　29.52%
  • Camphor　7.25%
  • 1,8-Cineole　4.35%
  • Terpinen-4-ol　3.24%
  • Borneol　2.55%
  • Lavandulyl acetate　2.29%
  • β-Caryophyllene　1.37%
  • β-Farnesene　1.03%
  • Other components　13.12%

Functions and Efficacies

1,8-Cineole

1,8-Cineole
  • IUPAC Name
    1,3,3-trimethyl-2-oxabicyclo[2.2.2]octane
  • Molecular Formula
    C15H26O
  • Molecular Weight
    154.25 g/mol
  • CAS No.
    470-82-6
  • Structure
    Monocyclic monoterpene ether

Functions and Efficacies of 1,8-Cineole

in slico in vitro ex vivo in vivo
Non-clinical Clinical
Mice Rats Guinea Pigs Insects Rabbits Human
Anti-inflammatory Effects ○
Deodorizing Effects
Anti-malaria Effects ○

Anti-inflammatory Effects

A study reported that in mice with inflammation in the leg, swelling was concentration-dependently reduced in the 1,8-cineole-treated group.1)

Deodorizing Effects

A study reported that when common odorants like skatole and 3-methylbutanoic acid were stored in a sealed container with 1,8-cineole, the odorant components were significantly diminished.2)

Antimalarial Effects

A study reported that the addition of 1,8-cineole reduced the number of infected cells in malaria-infected erythrocytes. Furthermore, it was found to inhibit the intracellular growth of Plasmodium falciparum and mitigate the brain edema caused by the infection3)

  • 1)Yin et al., Br J Pharmacol., 2019
  • 2)Henmi et al., J. Japan Association on Odor Environment, 2020
  • 3)Santos et al., plos one, 2022

Linalool

Linalool
  • IUPAC Name
    3,7-Dimethylocta-1,6-dien-3-ol
  • Molecular Formula
    C10H18O
  • Molecular Weight
    154.25 g/mol
  • CAS No.
    78-70-6
  • Structure
    Monoterpene alcohol

Functions and Efficacies of Linalool

in slico in vitro ex vivo in vivo
Non-clinical Clinical
Mice Rats Guinea Pigs Insects Rabbits Human
Anti-inflammatory Effects ○
Stress Reduction ○ ○
Anti-oxidant Effects ○

Anti-inflammatory Effects

A study reported that linalool reduced hindlimb edema in rats induced by carrageenan administration. 1)

Stress Reduction

A study reported that linalool treatment increased the time it took for mice to escape to a dark room when under light stress. Additionally, it reduced the number and duration of attacks on other mice in a confined room, indicating its stress-reducing effects.2) Linalool inhalation was observed to reverse gene expression alterations in the hypothalamus associated with stress response in mice.3) Numerous studies have documented the stress-reducing capabilities of linalool.4)5)6)

Anti-oxidant Effects

A study reported that the addition of linalool was found to suppress the generation of reactive oxygen species (ROS) induced by UV irradiation in human skin fibroblasts.7)

  • 1)Peana et al., Phytomedicine, 2002
  • 2)Linck et al., Phytomedicine, 2010
  • 3)Yoshida et al., Neuroscience Letters, 2017
  • 4)Harada et al., Frontiers in Behavioral Neuroscience, 2018
  • 5)Souto-Maior et al., Pharmacology Biochemistry and Behavior, 2011
  • 6)Weston-Green et al., Frontiers in Scichiatry, 2021
  • 7)Gunaseelan et al., Plos One, 2017

IFRA

Linalool：
Oxidized linalool can cause dermal sensitization. For essential oils with a high linalool content, it is advisable to use only when the level of peroxides is maintained at a minimum (20 mol/l) through the incorporation of antioxidants.

※Only information for selected components are shown here.

References
Jennie Harding [Handbook of Essential Oil and Plant Oil] Tokyo-do Publishing, 2010.
Shinichiro Otsuki/Yukiko Ozaki [Scientific Name Etymology Dictionary of Herbs] Tokyo-do Publishing, 2009.
Jennie Harding [Illustrated Reference Book of Herbs] Sancho Publishing, 2012.
Freddy Ghozland/Xavier Fernandez [L’Herbier Parfume] Hara Publishing, 2013.
Kyohei Mikami [Comprehensive Guide to Essential Oils] Fragrance Journal, 2010.
Yuzuru Ogura [Dictionary of Plants] Tokyo-do Publishing, 1957.
Nobuo Ohashi [Dictionary of Medical Herbs] Tokyo-do Publishing, 2016.
Wanda Sellar [The directory of essential oils] Fragrance Journal, 1992.
Aroma Environment Association of Japan [AEAJ Aromatherapy Certification Official Textbook grade1&2] Sekaibunka, 1999.
Robert Tissearand [Essential Oil Safety] Fragrance Journal, 2018.
Ayako Berg [Aromatherapy Essential Oil Dictionary] Seibido Shuppan, 2022.
Azusa Annells [Enjoying Fragrance: An Illustrated Book of Aromas with Characteristics]Natsumesha CO.,LTD., 2023
International Fragrance Association, Linalool, 2004.
(All written in or translated to Japanese.)
Supervisor
Yamamoto Perfumery co., ltd.

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